The first results of the PATCH/STAMPEDE trial are now published. Click here to see the paper!
Estradiol and ADT: Lessons from Lived Experience Videos
Mission Statement
Our mission is to educate patients and clinicians about the benefits and risks of using transdermal estradiol (tE2) for men receiving Androgen Deprivation Therapy (ADT) for prostate cancer. Our main goal is to secure FDA and NCCN approval for tE2 ADT as a Standard of Care for these patients.
Background
Recently, findings from the PATCH/STAMPEDE trial in the UK indicate that estradiol tE2 provides as good survival for prostate cancer (PCa) patients when used for androgen deprivation therapy (ADT) as the standard, approved drugs for androgen suppression. Furthermore, the PATCH/STAMPEDE research team previously demonstrated that patients have overall better quality of life when on tE2. Patients have, for example, significantly fewer hot flashes, better sleep, less fatigue, and lower risk of osteoporosis.
There are, however, no tE2 products on the market that have been tested and licensed for men with prostate cancer.
What are we doing?
Research…
- on prostate cancer patients’ interest in alternative forms of ADT.
- on the costs and benefits of various tE2 products on the market, and ways to make tE2 products both cheaper and more available to prostate cancer patients.
- in collaboration with scientists in the USA and UK, we are studying the quality of life benefits of estradiol for men on ADT.
Outreach to…
- patients via support organization in Canada the USA, and beyond, with in-person presentations and chat group participation.
- physicians through individual contacts and professional medical societies to inform them of the survival and quality of life benefits of ADT with tE2.
- Pharma to encourage their development of tE2 products, then testing and licensing the products so they can become officially approved standards of care for prostate cancer patients.
Fund raising…
- to generate enough funding through private and public donations to enable the creation and license of one or more tE2 products for men with prostate cancer.
Estradiol Initiative Summer Studentships
The Estradiol Initiative now offers Summer Studentships, which provide a small amount of financial support for up to 16 hours per week. We are looking for commitments of two months or more. The
tasks would ideally be in line with the students’ long-term goals. The studentships are for university students in Canada. Applicants should have an excellent academic record, with a minimum GPA of 3.5.
We are particularly searching for students with interests and skills in the following areas:
- Project management, accounting, business planning and economic analyses.
- Media skills in copy editing, video production and editing (e.g., short videos for social media posts and YouTube), and webpage design using WordPress.com.
- Medical research on prostate cancer patients’ quality of life
- Healthcare funding at the provincial and national level
- Journalism and marketing
If you wish to apply, familiarize yourself with the Estradiol Initiative by reviewing our website https://estradiolinitiative.org/. Then send us a one-to-two-page letter detailing your interests and how those interests and your skills align with the Estradiol Initiative’s activities and goals.
We welcome applicants’ ideas and suggestions about: 1) how to improve the Estradiol Initiative website, and 2) how to get the word out on transdermal estradiol as an option for treating prostate cancer patients!
Email application letters along with an updated transcript (unofficial transcripts are accepted) to: Carly Sears
“The contributors to this website have no Conflicts of Interest and they do not receive any money from selling estradiol products or from corporate sponsorships.”